Type I interferon signaling induces melanoma cell-intrinsic PD-1 and its inhibition antagonizes immune checkpoint blockade

Julia Holzgruber; Christina Martins; Zsofi Kulcsar; Alexandra Duplaine; Erik Rasbach; Wolfram Hötzenecker; Tobias Schatton; et al.

doi:10.1038/s41467-024-51496-2

Type I interferon signaling induces melanoma cell-intrinsic PD-1 and its inhibition antagonizes immune checkpoint blockade

Julia Holzgruber
, Christina Martins
, Zsofi Kulcsar
, Alexandra Duplaine
, Erik Rasbach
, Wolfram Hötzenecker
, Tobias Schatton
, et al.

Department of Dermatology and Venereology

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	7165
Number of pages	16
Journal	Nature Communications
Volume	15
Issue number	1
DOIs	https://doi.org/10.1038/s41467-024-51496-2
Publication status	Published - 26 Aug 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Fields of science

303 Health Sciences
304 Medical Biotechnology
305 Other Human Medicine, Health Sciences
301 Medical-Theoretical Sciences, Pharmacy
302 Clinical Medicine
302087 Venereology
302011 Dermatology

Access to Document

10.1038/s41467-024-51496-2

Cite this

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title = "Type I interferon signaling induces melanoma cell-intrinsic PD-1 and its inhibition antagonizes immune checkpoint blockade",

author = "Julia Holzgruber and Christina Martins and Zsofi Kulcsar and Alexandra Duplaine and Erik Rasbach and Wolfram H{\"o}tzenecker and Tobias Schatton and \{et al.\}",

year = "2024",

month = aug,

day = "26",

doi = "10.1038/s41467-024-51496-2",

language = "English",

volume = "15",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Springer Nature Limited",

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}

TY - JOUR

T1 - Type I interferon signaling induces melanoma cell-intrinsic PD-1 and its inhibition antagonizes immune checkpoint blockade

AU - Holzgruber, Julia

AU - Martins, Christina

AU - Kulcsar, Zsofi

AU - Duplaine, Alexandra

AU - Rasbach, Erik

AU - Hötzenecker, Wolfram

AU - Schatton, Tobias

AU - et al., null

PY - 2024/8/26

Y1 - 2024/8/26

UR - https://www.nature.com/articles/s41467-024-51496-2#author-information

UR - https://www.scopus.com/pages/publications/85202034982

U2 - 10.1038/s41467-024-51496-2

DO - 10.1038/s41467-024-51496-2

M3 - Article

C2 - 39187481

SN - 2041-1723

VL - 15

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 7165

ER -

Type I interferon signaling induces melanoma cell-intrinsic PD-1 and its inhibition antagonizes immune checkpoint blockade

UN SDGs

Fields of science

Access to Document

Other files and links

Cite this