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SensApp: a FET-open project for developing a supersensor able to detect Alzheimer's disease biomarkers in blood

  • Romina Rega
  • , Martina Mugnano
  • , Danila del Giudice
  • , Simona Itri
  • , Volodymyr Tkachenko
  • , Veronica Vespini
  • , Sara Coppola
  • , Pietro Ferraro
  • , Heidi Ottevaere
  • , Yunfeng Nie
  • , Sanna Uusitalo
  • , Reinhard Schwödiauer
  • , Martin Kaltenbrunner
  • , Markku Känsäkoski
  • , Emanuela Mazzon
  • , Pier Luca Maffettone
  • , Gaetano D'Avino
  • , Simonetta Grilli

Research output: Chapter in Book/Report/Conference proceedingConference proceedingspeer-review

Abstract

The goal of the SensApp FET-Open project is to develop an innovative super-sensor that will be able to detect Alzheimer’s disease (AD) biomarkers (β-amyloid, Tau and pTAU) in peripheral blood. Considering that nowadays an accurate diagnosis of AD requires the highly invasive withdrawal and analysis of cerebrospinal fluid, SensApp will represent a breakthrough in the field of AD diagnosis thanks to the ability to detect the early stage of the disease by a simple blood collection. We call Droplet-Split-and-Stack (DSS) the new technology that will emerge from SensApp. The achievement of SensApp goal is enabled by the interdisciplinary cooperation between different research institutions and one company involved in the key fields of the project, Vrije Universiteit Brussels, VTT Technical Research Centre of Finland, University of Linz, Ginolis Ltd, IRCCS Centre “Bonino Pulejo”, under the coordination of CNR-Institute of Applied Sciences and Intelligent Systems. This communication will illustrate the progress of the activities.
Original languageEnglish
Title of host publicationOptical Methods for Inspection, Characterization, and Imaging of Biomaterials V
EditorsPietro Ferraro, Simonetta Grilli, Monika Ritsch-Marte, Christoph K. Hitzenberger
PublisherSPIE
Pages1178605
Number of pages2
Volume11786
ISBN (Electronic)9781510644069
DOIs
Publication statusPublished - 2021

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume11786
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Fields of science

  • 103 Physics, Astronomy
  • 103008 Experimental physics
  • 103023 Polymer physics

JKU Focus areas

  • Sustainable Development: Responsible Technologies and Management

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