Repurposed high-throughput image assays enables biological activity prediction for drug discovery

Jaak Simm; Günter Klambauer; Adam Arany; Marvin Steijaert; Jörg Wegner; Emmanuel Gustin; Vladimir Chupakhin; Yolanda T. Chong; Jorge Vialard; Peter Buijnsters; Ingrid Velter; Alexander Vapirev; Shantanu Singh; Anne E. Carpenter; Roel Wuyts; Sepp Hochreiter; Yves Moreau; Hugo Ceulemans

doi:10.1016/j.chembiol.2018.01.015

Repurposed high-throughput image assays enables biological activity prediction for drug discovery

Jaak Simm
, Günter Klambauer
, Adam Arany
, Marvin Steijaert
, Jörg Wegner
, Emmanuel Gustin
, Vladimir Chupakhin
, Yolanda T. Chong
, Jorge Vialard
, Peter Buijnsters
, Ingrid Velter
, Alexander Vapirev
, Shantanu Singh
, Anne E. Carpenter
, Roel Wuyts
, Sepp Hochreiter
, Yves Moreau
, Hugo Ceulemans

Institute for Machine Learning

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	611-618
Number of pages	149
Journal	Cell Chemical Biology
Issue number	5
DOIs	https://doi.org/10.1016/j.chembiol.2018.01.015
Publication status	Published - 2018

Fields of science

305907 Medical statistics
202017 Embedded systems
202036 Sensor systems
101004 Biomathematics
101014 Numerical mathematics
101015 Operations research
101016 Optimisation
101017 Game theory
101018 Statistics
101019 Stochastics
101024 Probability theory
101026 Time series analysis
101027 Dynamical systems
101028 Mathematical modelling
101029 Mathematical statistics
101031 Approximation theory
102 Computer Sciences
102001 Artificial intelligence
102003 Image processing
102004 Bioinformatics
102013 Human-computer interaction
102018 Artificial neural networks
102019 Machine learning
102032 Computational intelligence
102033 Data mining
305901 Computer-aided diagnosis and therapy
305905 Medical informatics
202035 Robotics
202037 Signal processing
103029 Statistical physics
106005 Bioinformatics
106007 Biostatistics

JKU Focus areas

Digital Transformation

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10.1016/j.chembiol.2018.01.015

Cite this

Simm, J., Klambauer, G., Arany, A., Steijaert, M., Wegner, J., Gustin, E., Chupakhin, V., Chong, Y. T., Vialard, J., Buijnsters, P., Velter, I., Vapirev, A., Singh, S., Carpenter, A. E., Wuyts, R., Hochreiter, S., Moreau, Y., & Ceulemans, H. (2018). Repurposed high-throughput image assays enables biological activity prediction for drug discovery. Cell Chemical Biology, (5), 611-618. https://doi.org/10.1016/j.chembiol.2018.01.015

@article{636c089c059948328921ced3b6865c34,

title = "Repurposed high-throughput image assays enables biological activity prediction for drug discovery",

author = "Jaak Simm and G{\"u}nter Klambauer and Adam Arany and Marvin Steijaert and J{\"o}rg Wegner and Emmanuel Gustin and Vladimir Chupakhin and Chong, \{Yolanda T.\} and Jorge Vialard and Peter Buijnsters and Ingrid Velter and Alexander Vapirev and Shantanu Singh and Carpenter, \{Anne E.\} and Roel Wuyts and Sepp Hochreiter and Yves Moreau and Hugo Ceulemans",

year = "2018",

doi = "10.1016/j.chembiol.2018.01.015",

language = "English",

pages = "611--618",

journal = "Cell Chemical Biology",

issn = "2451-9448",

publisher = "Cell Press",

number = "5",

}

Simm, J, Klambauer, G, Arany, A, Steijaert, M, Wegner, J, Gustin, E, Chupakhin, V, Chong, YT, Vialard, J, Buijnsters, P, Velter, I, Vapirev, A, Singh, S, Carpenter, AE, Wuyts, R, Hochreiter, S, Moreau, Y & Ceulemans, H 2018, 'Repurposed high-throughput image assays enables biological activity prediction for drug discovery', Cell Chemical Biology, no. 5, pp. 611-618. https://doi.org/10.1016/j.chembiol.2018.01.015

TY - JOUR

T1 - Repurposed high-throughput image assays enables biological activity prediction for drug discovery

AU - Simm, Jaak

AU - Klambauer, Günter

AU - Arany, Adam

AU - Steijaert, Marvin

AU - Wegner, Jörg

AU - Gustin, Emmanuel

AU - Chupakhin, Vladimir

AU - Chong, Yolanda T.

AU - Vialard, Jorge

AU - Buijnsters, Peter

AU - Velter, Ingrid

AU - Vapirev, Alexander

AU - Singh, Shantanu

AU - Carpenter, Anne E.

AU - Wuyts, Roel

AU - Hochreiter, Sepp

AU - Moreau, Yves

AU - Ceulemans, Hugo

PY - 2018

Y1 - 2018

UR - https://www.scopus.com/pages/publications/85042602612

U2 - 10.1016/j.chembiol.2018.01.015

DO - 10.1016/j.chembiol.2018.01.015

M3 - Article

SN - 2451-9448

SP - 611

EP - 618

JO - Cell Chemical Biology

JF - Cell Chemical Biology

IS - 5

ER -

Repurposed high-throughput image assays enables biological activity prediction for drug discovery

Fields of science

JKU Focus areas

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