Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis

Daniel Diaz-Gil; Gregor Gierlinger; Natalia Silva-Gomez; Lavinia Rech; Jesus Ortiz-Urbina; Kerstin Saraci; Sophia Koutsogiannaki; Cordula M. Wolf; Rainer G. Kozlik-Feldmann; Rudolf Mair; Juan M. Melero-Martin; Sitaram M. Emani; Guillermo García-Cardeña; Pedro J. del Nido; Ingeborg Friehs

doi:10.1016/j.jacbts.2025.03.014

Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis

Daniel Diaz-Gil
, Gregor Gierlinger
, Natalia Silva-Gomez
, Lavinia Rech
, Jesus Ortiz-Urbina
, Kerstin Saraci
, Sophia Koutsogiannaki
, Cordula M. Wolf
, Rainer G. Kozlik-Feldmann
, Rudolf Mair
, Juan M. Melero-Martin
, Sitaram M. Emani
, Guillermo García-Cardeña
, Pedro J. del Nido
, Ingeborg Friehs^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	101282
Journal	JACC: Basic to Translational Science
Volume	10
Issue number	9
DOIs	https://doi.org/10.1016/j.jacbts.2025.03.014
Publication status	Published - Sept 2025

Fields of science

305 Other Human Medicine, Health Sciences
302 Clinical Medicine
303 Health Sciences
304 Medical Biotechnology
301 Medical-Theoretical Sciences, Pharmacy
302035 Paediatrics and adolescent medicine
302032 Cardiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jacbts.2025.03.014

Cite this

Diaz-Gil, D., Gierlinger, G., Silva-Gomez, N., Rech, L., Ortiz-Urbina, J., Saraci, K., Koutsogiannaki, S., Wolf, C. M., Kozlik-Feldmann, R. G., Mair, R., Melero-Martin, J. M., Emani, S. M., García-Cardeña, G., del Nido, P. J., & Friehs, I. (2025). Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis. JACC: Basic to Translational Science, 10(9), Article 101282. https://doi.org/10.1016/j.jacbts.2025.03.014

@article{ccfb49f86ce840c78afe39b2942b3a1b,

title = "Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis",

keywords = "atorvastatin, congenital heart disease, endocardial fibroelastosis, endothelial-mesenchymal transition, hypoplastic left heart syndrome",

author = "Daniel Diaz-Gil and Gregor Gierlinger and Natalia Silva-Gomez and Lavinia Rech and Jesus Ortiz-Urbina and Kerstin Saraci and Sophia Koutsogiannaki and Wolf, \{Cordula M.\} and Kozlik-Feldmann, \{Rainer G.\} and Rudolf Mair and Melero-Martin, \{Juan M.\} and Emani, \{Sitaram M.\} and Guillermo Garc{\'i}a-Carde{\~n}a and \{del Nido\}, \{Pedro J.\} and Ingeborg Friehs",

note = "Publisher Copyright: {\textcopyright} 2025 The Authors",

year = "2025",

month = sep,

doi = "10.1016/j.jacbts.2025.03.014",

language = "English",

volume = "10",

journal = "JACC: Basic to Translational Science",

issn = "2452-302X",

number = "9",

}

Diaz-Gil, D, Gierlinger, G, Silva-Gomez, N, Rech, L, Ortiz-Urbina, J, Saraci, K, Koutsogiannaki, S, Wolf, CM, Kozlik-Feldmann, RG, Mair, R, Melero-Martin, JM, Emani, SM, García-Cardeña, G, del Nido, PJ & Friehs, I 2025, 'Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis', JACC: Basic to Translational Science, vol. 10, no. 9, 101282. https://doi.org/10.1016/j.jacbts.2025.03.014

TY - JOUR

T1 - Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis

AU - Diaz-Gil, Daniel

AU - Gierlinger, Gregor

AU - Silva-Gomez, Natalia

AU - Rech, Lavinia

AU - Ortiz-Urbina, Jesus

AU - Saraci, Kerstin

AU - Koutsogiannaki, Sophia

AU - Wolf, Cordula M.

AU - Kozlik-Feldmann, Rainer G.

AU - Mair, Rudolf

AU - Melero-Martin, Juan M.

AU - Emani, Sitaram M.

AU - García-Cardeña, Guillermo

AU - del Nido, Pedro J.

AU - Friehs, Ingeborg

PY - 2025/9

Y1 - 2025/9

KW - atorvastatin

KW - congenital heart disease

KW - endocardial fibroelastosis

KW - endothelial-mesenchymal transition

KW - hypoplastic left heart syndrome

UR - https://www.scopus.com/pages/publications/105012118929

U2 - 10.1016/j.jacbts.2025.03.014

DO - 10.1016/j.jacbts.2025.03.014

M3 - Article

AN - SCOPUS:105012118929

SN - 2452-302X

VL - 10

JO - JACC: Basic to Translational Science

JF - JACC: Basic to Translational Science

IS - 9

M1 - 101282

ER -

Preclinical Assessment of Atorvastatin for Treatment of Endocardial Fibroelastosis

Fields of science

UN SDGs

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