Long and short lipid molecules experience the same interleaflet drag in lipid bilayers

Andreas Horner, A. Sergey Akimov, Peter Pohl

Research output: Contribution to journalArticlepeer-review

Abstract

Membrane interleaflet viscosity N e affects tether formation, phase separation into domains, cell shape changes, and budding. Contrary to the expected contribution to interleaflet coupling from interdigitation, the slide of lipid patches in opposing monolayers conferred the same value N e~3x10^9 Jsm^-4 for the friction experienced by the ends of both short and long chain fluorescent lipid analogues. Consistent with the weak dependence of the translational diffusion coefficient on lipid length, the in-layer viscosity was, albeit length dependent, much smaller than N e.
Original languageEnglish
Article number268101
Pages (from-to)268101
Number of pages5
JournalPhysical Review Letters
Volume110
Issue number26
DOIs
Publication statusPublished - Jun 2013

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