TY - JOUR
T1 - Hidradenoma Papilliferum
T2 - A Clinicopathologic Study of 264 Tumors From 261 Patients, With Emphasis on Mammary-Type Alterations
AU - Konstantinova, Anastasia M
AU - Michal, Michal
AU - Kacerovska, Denisa
AU - Spagnolo, Dominic V
AU - Stewart, Colin J
AU - Kutzner, Heinz
AU - Zelger, Bernhard
AU - Plaza, Jose A
AU - Denisjuk, Natalja
AU - Hejda, Vaclav
AU - Shelekhova, Ksenya
AU - Bisceglia, Michele
AU - Danis, Dusan
AU - Zamecnik, Michal
AU - Kerl, Katrin
AU - Guenova, Emmanuella
AU - Kazakov, Dmitry V
PY - 2016/8
Y1 - 2016/8
N2 - Hidradenoma papilliferum (HP), also known as papillary hidradenoma, is the most common benign lesion of the female anogenital area derived from anogenital mammary-like glands (AGMLG). HP can be viewed conceptually as the cutaneous counterpart of mammary intraductal papilloma. The authors have studied 264 cases of HP, detailing various changes in the tumor and adjacent AGMLG, with emphasis on mammary-type alterations. In many HP, the authors noticed changes typical for benign breast lesions, such as sclerosing adenosis-like changes, usual, and atypical ductal hyperplasia. Almost in a third of cases, remnants of AGMLG adjacent to the lesion were evident, manifesting columnar changes reminiscent of those seen in breast lesions. This study shows that the histopathological changes in HP run a broad spectrum comparable with that in the mammary counterpart and benign breast disease.
AB - Hidradenoma papilliferum (HP), also known as papillary hidradenoma, is the most common benign lesion of the female anogenital area derived from anogenital mammary-like glands (AGMLG). HP can be viewed conceptually as the cutaneous counterpart of mammary intraductal papilloma. The authors have studied 264 cases of HP, detailing various changes in the tumor and adjacent AGMLG, with emphasis on mammary-type alterations. In many HP, the authors noticed changes typical for benign breast lesions, such as sclerosing adenosis-like changes, usual, and atypical ductal hyperplasia. Almost in a third of cases, remnants of AGMLG adjacent to the lesion were evident, manifesting columnar changes reminiscent of those seen in breast lesions. This study shows that the histopathological changes in HP run a broad spectrum comparable with that in the mammary counterpart and benign breast disease.
KW - Acrospiroma/pathology
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Anal Canal/pathology
KW - Anal Gland Neoplasms/pathology
KW - Biopsy
KW - Female
KW - Humans
KW - Mammary Glands, Human/pathology
KW - Middle Aged
KW - Predictive Value of Tests
KW - Sweat Gland Neoplasms/pathology
KW - Vulvar Neoplasms/pathology
KW - Young Adult
UR - https://www.scopus.com/pages/publications/84957837125
U2 - 10.1097/DAD.0000000000000495
DO - 10.1097/DAD.0000000000000495
M3 - Article
C2 - 26863059
SN - 0193-1091
VL - 38
SP - 598
EP - 607
JO - The American Journal of dermatopathology
JF - The American Journal of dermatopathology
IS - 8
ER -
