Dexamethasone and dexamethasone phosphate detected by 1H and 19F NMR spectroscopy in the aqueous humour

Anna Dybdahl; Ingrid Gribbestad; Jostein Krane; Anna Midelfart; Norbert Müller; Beathe Sitter

Dexamethasone and dexamethasone phosphate detected by 1H and 19F NMR spectroscopy in the aqueous humour

Anna Dybdahl, Ingrid Gribbestad, Jostein Krane, Anna Midelfart, Norbert Müller, Beathe Sitter

Institute of Organic Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

NMR spectroscopy appears to be a valuable method for studying dexamethason metabolism and penetration in ocular tissues. It provides simultaneous detection of both the drug metabolites and other substances in the sample and offers a complemtary approach to other analytical methods.

Original language	English
Number of pages	9
Journal	Investigative Ophthalmology & Visual Science
Publication status	Published - Mar 1997

Fields of science

104002 Analytical chemistry
106002 Biochemistry
301206 Pharmacology
301303 Medical biochemistry
302007 Ophthalmology

Application of NMR-spectroscopy in pharmacology
N., N. (PI)
01.11.1985 → …
Project: Other › Project from scientific scope of research unit

Cite this

@article{c974fc96999f40b3907efa47015511af,

title = "Dexamethasone and dexamethasone phosphate detected by 1H and 19F NMR spectroscopy in the aqueous humour",

abstract = "NMR spectroscopy appears to be a valuable method for studying dexamethason metabolism and penetration in ocular tissues. It provides simultaneous detection of both the drug metabolites and other substances in the sample and offers a complemtary approach to other analytical methods.",

author = "Anna Dybdahl and Ingrid Gribbestad and Jostein Krane and Anna Midelfart and Norbert M{\"u}ller and Beathe Sitter",

year = "1997",

month = mar,

language = "English",

journal = "Investigative Ophthalmology & Visual Science",

issn = "1552-5783",

publisher = "Association for Research in Vision and Ophthalmology (ARVO)",

}

TY - JOUR

T1 - Dexamethasone and dexamethasone phosphate detected by 1H and 19F NMR spectroscopy in the aqueous humour

AU - Dybdahl, Anna

AU - Gribbestad, Ingrid

AU - Krane, Jostein

AU - Midelfart, Anna

AU - Müller, Norbert

AU - Sitter, Beathe

PY - 1997/3

Y1 - 1997/3

N2 - NMR spectroscopy appears to be a valuable method for studying dexamethason metabolism and penetration in ocular tissues. It provides simultaneous detection of both the drug metabolites and other substances in the sample and offers a complemtary approach to other analytical methods.

AB - NMR spectroscopy appears to be a valuable method for studying dexamethason metabolism and penetration in ocular tissues. It provides simultaneous detection of both the drug metabolites and other substances in the sample and offers a complemtary approach to other analytical methods.

M3 - Article

SN - 1552-5783

JO - Investigative Ophthalmology & Visual Science

JF - Investigative Ophthalmology & Visual Science

ER -

Dexamethasone and dexamethasone phosphate detected by 1H and 19F NMR spectroscopy in the aqueous humour

Abstract

Fields of science

Projects

Application of NMR-spectroscopy in pharmacology

Cite this