cn.FARMS - a probabilistic model to detect DNA copy numbers

Djork-Arné Clevert, Marianne Tuefferd, An De Bondt, Willem Talloen, Hinrich W.H. Göhlmann, Sepp Hochreiter

Research output: Chapter in Book/Report/Conference proceedingConference proceedingspeer-review

Abstract

High-density oligonucleotide microarrays, and in particular Affymetrix Mapping or SNP arrays offer the opportunity to get a genome-wide view on copy number alterations and are increasingly used in oncology. We present a probabilistic latent variable model, called cn.FARMS, that takes probe level information to model the the correlation in the observed data.
Original languageEnglish
Title of host publicationISMB 2009 Proceedings
Number of pages1
Publication statusPublished - Jun 2009

Fields of science

  • 101004 Biomathematics
  • 101027 Dynamical systems
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  • 102 Computer Sciences
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  • 305901 Computer-aided diagnosis and therapy
  • 305905 Medical informatics
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  • 102032 Computational intelligence
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  • 101031 Approximation theory

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