Capsular bag performance of an aspheric hydrophobic IOL after conventional phacoemulsification or femtosecond laser-assisted cataract surgery: 12-month results of a randomized prospective study

PURPOSE: To evaluate a new hydrophobic aspheric intraocular lens (IOL) regarding its refractive and position stability after conventional (CCS) or femtosecond laser-assisted cataract surgery (FLACS).

METHODS: All patients received the same IOL (CT LUCIA 621P, Carl Zeiss Meditec AG, Germany). Both eyes of each patient were randomized, with one eye assigned to the FLACS group and the other eye to the CCS group. One, 6 and 12 months after surgery, 2 different swept-source optical coherence tomography measurements (IOLMaster 700, Carl Zeiss Meditec AG, Germany and CASIA-2, Tomey GmbH, Japan) were performed as well as subjective refraction, best corrected (BCDVA) and uncorrected visual acuity (UDVA).

RESULTS: A total of 74 eyes of 37 patients were included in this study. Mean postoperative BCDVA for the FLACS and CCS group was - 0.08 ± 0.08 logMAR and 0.08 ± 0.07 logMAR, respectively. Overall, mean absolute error (MAE) and mean error (ME) was 0.48 ± 0.38dpt and 0.42 ± 0.44dpt respectively with no differences between groups (p = 0.559 and p = 0.786). Overall, tilt magnitude was stable in all groups over the course of 12 months with a mean tilt magnitude of 4.48 ± 2.48° at 12 months. Postoperative patient satisfaction was high with 97.3% of all patients very or fairly satisfied with the outcome.

CONCLUSION: There was no significant difference between groups regarding postoperative stability and capsular bag performance as well as refractive error over the course of 12 months. The CT LUCIA 621P demonstrated good efficacy, safety and stability. No issues regarding biocompatibility of the IOL material were observed.