Abstract
The present invention relates in general to the field of targeted drug delivery of anti-cancer drugs. More precisely, the present invention concerns polymer drug conjugates, namely, conjugates of poly(organo)phosphazenes and anti-cancer drugs, wherein the conjugates are suitable to selectively release anti-cancer drugs in tumor tissue. In addition, the present invention relates to a method for manufacturing such poly(organo)phosphazene molecule conjugates, to poly(organo)phosphazene molecule conjugates for use in medicine, in particular, to poly(organo)phosphazene molecule conjugates for use in the treatment of cancer, and to pharmaceutical compositions comprising such poly(organo)phosphazene molecule conjugates.
| Original language | English |
|---|---|
| Patent number | US9192677B2 |
| Publication status | Published - 24 Nov 2015 |
Fields of science
- 301207 Pharmaceutical chemistry
- 210004 Nanomaterials
- 104019 Polymer sciences
- 104018 Polymer chemistry
- 104002 Analytical chemistry
- 104 Chemistry
- 104016 Photochemistry
- 204002 Chemical reaction engineering
- 301904 Cancer research
- 301305 Medical chemistry
- 104015 Organic chemistry
- 104014 Surface chemistry
- 104011 Materials chemistry
- 104010 Macromolecular chemistry
- 107002 Bionics
- 302009 Chemotherapy
- 304007 Tissue engineering
- 104008 Catalysis
- 106002 Biochemistry
JKU Focus areas
- Sustainable Development: Responsible Technologies and Management
