A carbohydrate-linked hypericinic photosensitizing agent

Joachim Zuschrader; Wolfgang Schöfberger; Heinz Falk

doi:10.1007/s00706-008-0928-y

A carbohydrate-linked hypericinic photosensitizing agent

Joachim Zuschrader, Wolfgang Schöfberger, Heinz Falk

Research output: Contribution to journal › Article › peer-review

Abstract

With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXalpha to be even better than those of the parent compound hypericin. Investigations on binding-interactions with DNA showed promising results as well.

Original language	English
Pages (from-to)	1387-1390
Number of pages	4
Journal	Monatshefte für Chemie - Chemical Monthly
Volume	139
Issue number	11
DOIs	https://doi.org/10.1007/s00706-008-0928-y
Publication status	Published - Nov 2008

Fields of science

104015 Organic chemistry

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10.1007/s00706-008-0928-y

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title = "A carbohydrate-linked hypericinic photosensitizing agent",

abstract = "With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXalpha to be even better than those of the parent compound hypericin. Investigations on binding-interactions with DNA showed promising results as well.",

author = "Joachim Zuschrader and Wolfgang Sch{\"o}fberger and Heinz Falk",

year = "2008",

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doi = "10.1007/s00706-008-0928-y",

language = "English",

volume = "139",

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T1 - A carbohydrate-linked hypericinic photosensitizing agent

AU - Zuschrader, Joachim

AU - Schöfberger, Wolfgang

AU - Falk, Heinz

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Y1 - 2008/11

N2 - With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXalpha to be even better than those of the parent compound hypericin. Investigations on binding-interactions with DNA showed promising results as well.

AB - With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXalpha to be even better than those of the parent compound hypericin. Investigations on binding-interactions with DNA showed promising results as well.

UR - https://www.scopus.com/pages/publications/55349091715

U2 - 10.1007/s00706-008-0928-y

DO - 10.1007/s00706-008-0928-y

M3 - Article

SN - 0026-9247

VL - 139

SP - 1387

EP - 1390

JO - Monatshefte für Chemie - Chemical Monthly

JF - Monatshefte für Chemie - Chemical Monthly

IS - 11

ER -

A carbohydrate-linked hypericinic photosensitizing agent

Abstract

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Solid state and Liquid NMR of biomolecular Metalcomplexes

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A carbohydrate-linked hypericinic photosensitizing agent

Abstract

Fields of science

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Projects

Solid state and Liquid NMR of biomolecular Metalcomplexes

Cite this