Research output per year
Research output per year
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STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening
Najjar, H., Weiß, S., Horvath, F., Hopl, V., Tiffner, A., Höbarth, L., Söllner, J., Fröhlich, M., Prantl, M., Müller, N., Nazarenko, Y., Harant, S., Weissenböck, L., Grabmayr, H., Sallinger, M., Maltan, L., Echefu, L. V., Radiskovic, T., Leopold, M. & Lindinger, S. & 5 others, , 18 Jun 2025, In: Cell Reports Physical Science. 6, 6, 23 p., 102623.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation mechanisms and structural dynamics of STIM proteins
Sallinger, M., Grabmayr, H., Humer, C., Bonhenry, D., Romanin, C., Schindl, R. & Derler, I., 15 Apr 2024, In: The Journal of Physiology. 602, 8, p. 1475-1507 33 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic code expansion, an emerging tool in the Ca2+ ion channel field
Söllner, J. & Derler, I., 15 Jul 2024, In: Journal of Physiology. 602, 14, p. 3297-3313 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Water in peripheral TM-interfaces of Orai1-channels triggers pore opening
Hopl, V., Tiffner, A., Wutscher, A., Sallinger, M., Grabmayr, H., Prantl, M., Fröhlich, M., Söllner, J., Weiß, S., Najjar, H., Nazarenko, Y., Harant, S., Krisko, N., Fahrner, M., Humer, C., Höglinger, C., Krobath, H., Bonhenry, D. & Derler, I., 16 Nov 2024, In: Communications Biology. 7, 1, 16 p., 1522.Research output: Contribution to journal › Article
Open Access -
CRAC and SK Channels: Their Molecular Mechanisms Associated with Cancer Cell Development
Tiffner, A., Hopl, V. & Derler, I., Jan 2023, In: Cancers. 15, 1, p. Cancers 2023, 15(1), 101 49 p., 101.Research output: Contribution to journal › Article
Open Access
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Novel insights in CRAC Channels by genetic code expansion
Derler, I. (PI)
01.01.2023 → 31.12.2026
Project: Funded research › FWF - Austrian Science Fund
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Dynamik des Orai1-Kanals, die die Porenöffnung bestimmt
Derler, I. (PI)
01.10.2022 → 30.09.2026
Project: Funded research › FWF - Austrian Science Fund
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Role of cholesterol in the regulation of SK3 K+ currents
Derler, I. (Researcher)
01.09.2026 → 31.08.2030
Project: Funded research › FWF - Austrian Science Fund
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Wechselwirkung von CRAC und Ca2+ aktivierten K+ Ionenkanälen
Derler, I. (PI)
01.12.2020 → 31.12.2023
Project: Funded research › FWF - Austrian Science Fund
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Interplay of CRAC channels with Ca2+ activated K+ channels
Derler, I. (PI)
01.06.2020 → 31.05.2024
Project: Funded research › FWF - Austrian Science Fund
Activities
- 4 Poster presentation
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Constitutively active Orai TM mutants exhibit altered CRAC characteristics
Tiffner, A. (Speaker), Höglinger, C. (Speaker), Derler, I. (Speaker), Fahrner, M. (Speaker), Frischauf, I. (Speaker), Schindl, R. (Speaker), Muik, M. (Speaker) & Romanin, C. (Speaker)
15 Jun 2016Activity: Talk or presentation › Poster presentation › unknown
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A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca2+ permeation and SOCE-induced gene transcription
Frischauf, I. (Speaker), Zayats, V. (Speaker), Deix, M. (Speaker), Hochreiter, A. (Speaker), Jardin-Polo, I. (Speaker), Muik, M. (Speaker), Svobodova, B. (Speaker), Pammer, T. (Speaker), Litvinukova, M. (Speaker), Arumbakam, S. (Speaker), Derler, I. (Speaker), Bogeski, I. (Speaker), Romanin, C. (Speaker), Ettrich, R. (Speaker), Schindl, R. (Speaker) & Lackner, B. (Speaker)
29 Feb 2016Activity: Talk or presentation › Poster presentation › unknown
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NMR investigation and large scale overexpression of isotopically labeled STIM1OASF and Orai1loop2 protein fragments
Rathner, P. (Speaker), Derler, I. (Speaker), Romanin, C. (Speaker) & Müller, N. (Speaker)
05 Jul 2015Activity: Talk or presentation › Poster presentation › unknown
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Isoform-specific fine tuning of Orai protein function
Derler, I. (Speaker)
08 Jun 2015Activity: Talk or presentation › Poster presentation › unknown