Research output per year
Research output per year
Research output
- 5 Article
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Distances and charges along the Orai1 nexus-TM3 interface control STIM1 binding and pore opening
Söllner, J., Prantl, M., Najjar, H., Aichner, V., Suta, A. M., Nazarenko, Y., Zoric, D., Harant, S., Fröhlich, M., Radiskovic, T., Thallinger, D., Mairhofer, C., Nzegge, W., Weiß, S., Krobath, H., Waser, M. & Derler, I., 24 Feb 2026, In: Cell Reports. 45, 2, 1 p., 116940.Research output: Contribution to journal › Article › peer-review
Open Access -
STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening
Najjar, H., Weiß, S., Horvath, F., Hopl, V., Tiffner, A., Höbarth, L., Söllner, J., Fröhlich, M., Prantl, M., Müller, N., Nazarenko, Y., Harant, S., Weissenböck, L., Grabmayr, H., Sallinger, M., Maltan, L., Echefu, L. V., Radiskovic, T., Leopold, M. & Lindinger, S. & 5 others, , 18 Jun 2025, In: Cell Reports Physical Science. 6, 6, 23 p., 102623.Research output: Contribution to journal › Article › peer-review
Open Access -
Water in peripheral TM-interfaces of Orai1-channels triggers pore opening
Hopl, V., Tiffner, A., Wutscher, A., Sallinger, M., Grabmayr, H., Prantl, M., Fröhlich, M., Söllner, J., Weiß, S., Najjar, H., Nazarenko, Y., Harant, S., Krisko, N., Fahrner, M., Humer, C., Höglinger, C., Krobath, H., Bonhenry, D. & Derler, I., 16 Nov 2024, In: Communications Biology. 7, 1, 16 p., 1522.Research output: Contribution to journal › Article
Open Access -
Photocrosslinking-induced CRAC channel-like Orai1 activation independent of STIM1
Maltan, L., Weiß, S., Najjar, H., Leopold, M., Lindinger, S., Höglinger, C., Höbarth, L., Sallinger, M., Grabmayr, H., Berlansky, S., Krivic, D., Hopl, V., Blaimschein, A., Fahrner, M., Frischauf, I., Tiffner, A. & Derler, I., 08 Mar 2023, In: Nature Communications. 14, 1, p. 1286 14 p., 1286.Research output: Contribution to journal › Article › peer-review
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Deciphering Molecular Mechanisms and Intervening in Physiological and Pathophysiological Processes of Ca 2+ Signaling Mechanisms Using Optogenetic Tools
Maltan, L., Najjar, H., Tiffner, A. & Derler, I., 28 Nov 2021, In: Cells. 10, 12, p. 3340 47 p., 3340.Research output: Contribution to journal › Article › peer-review
Projects
- 1 Active
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Study minimal motions and drug binding of Orai isoforms
Najjar, H. (PI), Waser, M. (Researcher), Himmelsbach, M. (Researcher), Renger, T. (Researcher), Coin, I. (Researcher), Ikura, M. (Researcher) & Stathopulos, P. (Researcher)
01.05.2026 → 30.11.2029
Project: Funded research › FWF - Austrian Science Fund