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No photo of Birgit Karner-Höger

Birgit Karner-Höger

Dr.

  • Institute of Pharmacology
 https://orcid.org/0000-0001-7491-9405
  • Emailbirgit.karner-hoegerjkuat
  • Overview
  • Network
  • Research output (8)
  • Projects (2)
  • Activities (16)
  • Prizes (3)
  • Supervised Work (2)

Research output

  • 5 Article
  • 1 Conference proceedings
  • 1 Popular science article
  • 1 Preprint

Research output per year

Research output per year

  • Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes

    Kalinichenko, A., Huemer, J., Humer, T., Haimel, M., Svaton, M., Socquet-Juglard, N., Casoni, G. P., Prakash, C., von der Linde, M., Pazmandi, J., van de Wetering, C., Nunez-Fontarnau, J., Kamnev, A., Giuliani, S., Jaeger, M. G., Hahn, E., Dobner, S., Rukavina, A., Sylvander, E. & Seigner, J. & 11 others, Rashkova, C., Hoeger, B., Traxlmayr, M. W., Lehner, M., Bryceson, Y. T., Saarela, J., Hannich, T., Castanon, I., Winter, G., Dupré, L. & Boztug, K., 17 Oct 2025, In: Science immunology. 10, 112, p. eado3825 eado3825.

    Research output: Contribution to journal › Article › peer-review

  • TRPM7 activity drives human CD4 T-cell activation and differentiation in a magnesium dependent manner

    Hoelting, K., Madlmayr, A., Höger, B., Lewitz, D., Weng, M., Haider, T., Duggan, M., Ross, R., Horgen, F. D., Sperandio, M., Dietrich, A., Gudermann, T. & Zierler, S., 07 Dec 2024, 53 p. (BioRxiv).

    Research output: Working paper and reports › Preprint

  • Inactivation of TRPM7 Kinase Targets AKT Signaling and Cyclooxygenase-2 Expression in Human CML Cells

    Höger, B., Nadolni, W., Hampe, S., Hoelting, K., Fraticelli, M., Zaborsky, N., Madlmayr, A., Sperrer, V., Fraticelli, L., Addington, L., Steinritz, D., Chubanov, V., Geisberger, R., Greil, R., Breit, A., Boekhoff, I., Gudermann, T. & Zierler, S., Sept 2023, In: Function. 4, 6, 11 p., zqad053.

    Research output: Contribution to journal › Article › peer-review

    Open Access
  • Ion Channels and Transporters in Immunity—Where do We Stand?

    Höger, B. & Zierler, S., 2023, In: Function. 4, 1, 3 p., zqac070.

    Research output: Contribution to journal › Article › peer-review

    Open Access
  • TRPM7 ion channel and kinase drives AKT signaling and immune-cell activation

    Höger, B., Madlmayr, A., Hölting, K., Nadolni, W., Lewitz, D., Haider, T., Hampe, S., Fraticelli, M., Chubanov, V., Sperandio, M., Boekhoff, I., Gudermann, T. & Zierler, S., Nov 2023, Intrinsic Activity. 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Conference proceedings › peer-review

View all 8 research outputs

Projects

  • 2 Active

Projects per year

  • Magnesium channel modulates T-cell cytotoxicity

    Zierler, S. (Researcher) & Karner-Höger, B. (PI)

    01.01.2024 → 18.02.2027

    Project: Funded research › Federal / regional / local authorities

  • Regulation zellulärer Toleranzmechanismen über Ionenkanäle in humanen Immunzellen und deren Subtypen

    Donnerer, J. (Researcher), Karner-Höger, B. (Researcher), Madlmayr, A. (Researcher), Sperrer, V. (Researcher), Steiner, P. (Researcher), Zierler, S. (PI), Hacker, S. (Researcher), Haider, T. (Researcher), Weng, M. (Researcher), Duggan, M. (Researcher), Eder, J. (Researcher), Horner, K. (Researcher), Platzer, R. (Researcher) & Wiesbauer, L. (Researcher)

    01.08.2022 → 31.07.2026

    Project: Clinical studies › Clinical Study (Academic - no third-party funds)

Activities

  • 5 Scientific society
  • 5 Contributed talk
  • 4 Poster presentation
  • 2 Board, Committee or Jury

Activities per year

  • Targeting TRPM7 to modulate chronic myeloid leukemia

    Karner-Höger, B. (Speaker)

    14 Mar 2024

    Activity: Talk or presentation › Poster presentation › science-to-science

  • TRPM7 ion channel and kinase drives AKT signaling and immune cell activation

    Karner-Höger, B. (Speaker)

    30 Sept 2023

    Activity: Talk or presentation › Poster presentation › science-to-science

  • TRPM7 ion channel and kinase drives AKT signaling and immune cell activation

    Karner-Höger, B. (Speaker)

    14 Sept 2023

    Activity: Talk or presentation › Contributed talk › science-to-science

  • TRPM7 ion channel-coupled protein kinase mediates AKT-dependent signaling in human immune cells and leukemia cells

    Karner-Höger, B. (Speaker)

    01 Aug 2023

    Activity: Talk or presentation › Poster presentation › science-to-science

  • TRPM7 kinase drives AKT signaling and COX-2 expression in human CML cells

    Karner-Höger, B. (Speaker)

    11 May 2023

    Activity: Talk or presentation › Contributed talk › science-to-science

View all 16 activities

Prizes

  • Influencing the activity of cancer-promoting phosphatase of regenerating liver (PRL)-3 by computationally supported development of small molecule inhibitors

    Höger, B. (Recipient), 2013

    Prize: Fellowship

  • Kepler Science Day award for oral presentation

    Karner-Höger, B. (Recipient), 2023

    Prize: Prize, award or honor

  • Novel modulators of CTLA-4 regulation and human autoimmunity

    Höger, B. (Recipient), 2020

    Prize: Fellowship

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