Numerical (CFD) simulation of polymer-drug distribution during injection moulding using OpenFOAM and SIGMASOFT

  • Herwig Juster (Speaker)
  • Straka, K. (Speaker)
  • Georg Steinbichler (Speaker)

    Activity: Talk or presentation › Poster presentation › unknown

    Description

    40% of all active pharmaceutical ingredients (APIs) can be considered poorly water soluble. New processes and formulations need to be developed to enhance the bioavailability of such substances. Injection moulding technique is used to fabricate drug dosage forms with enhanced solubility. The distribution homogeneity of the drug within the polymer matrix must be ensured by the end of the injection moulding process. The posterpresentation gives an overview of the CFD set-up for an amorphous solid dispersion of the plasticizer unit and the tablet injection mould.
    Period04 Apr 2013
    Event titleAustrian-Slovenian Polymer Meeting (ASPM) 2013
    Event typeConference
    LocationSloveniaShow on map

    Fields of science

    • 205012 Polymer processing
    • 203011 Lightweight design
    • 205011 Polymer engineering
    • 203013 Mechanical engineering
    • 203015 Mechatronics
    • 103032 Fluid mechanics
    • 205017 Materials engineering
    • 211909 Energy technology

    JKU Focus areas

    • Nano-, Bio- and Polymer-Systems: From Structure to Function
    • Engineering and Natural Sciences (in general)

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