Electrochromic shift calculations explain spectral tuning in light-sensitive proteins

Beschreibung

Rhodopsins are biological pigment-proteins found in photoreceptor cells of the retina. Within the framework of a quantum chemical/electrostatic calculation scheme that has recently been successfully applied to reveal the functional states of BLUF photoreceptors [1], we estimated absorption shifts of the retinal cofactor for a series of site-directed mutants. Our calculations accurately reproduce a series of spectroscopic data and eventually the variations of the maximal absorbance in the red- and green-sensitive visual pigments. [1] F. Collette et al., J. Phys. Chem. B 118, 11109 (2014).

Zeitraum	20 März 2015
Ereignistitel	79. Jahrestagung der DPG und DPG-Frühjahrstagung
Veranstaltungstyp	Konferenz
Ort	DeutschlandAuf Karte anzeigen